Pain Relief – Verum Viridi Moods CBD + CBDA – 10ml

CBD, CBDA and magnolia compounds

Hemp and magnolia are at the centre of Relief, a CBD + CBDA oil from Verum Viridi’s Moods collection. Its formulation brings together cannabinoids, the magnolia compounds honokiol and magnolol, sage, piperine and astaxanthin in an MCT oil base.

CBD and CBDA together

CBD and CBDA are closely related cannabinoids with distinct chemical structures. CBDA, short for cannabidiolic acid, occurs naturally in hemp and is the precursor from which CBD forms through decarboxylation—a chemical change accelerated by heat. Relief includes both forms.

CBDA has attracted research interest in its own right. In a study using rats, researchers investigated its effects on sensitivity to painful stimuli and inflammation, and identified a role for TRPV1, a receptor involved in sensory signalling. The results depended on how and when the compound was administered.

Honokiol and magnolol

Honokiol and magnolol are two characteristic compounds found in magnolia bark. They belong to the plant’s phenolic chemistry and are closely related to one another, with small differences in molecular structure.

Laboratory studies have investigated their antioxidant activity and their influence on inflammatory signalling. In one cell study, both compounds reduced the production of certain inflammatory messengers and affected NF-κB, a system involved in regulating the inflammatory response. These findings concern individual ingredients under experimental conditions; they do not establish the effects of the finished Relief oil.

The wider formulation

The blend also contains Salvia officinalis, the familiar aromatic sage, together with piperine, astaxanthin, limonene and vitamin E. Piperine is the characteristic alkaloid of black pepper. Astaxanthin belongs to the carotenoid family of pigments, while limonene is a terpene widely found in plant essential oils, including those of citrus peel.

MCT oil provides the carrier for the formulation. Relief’s particular combination of cannabinoids, magnolia compounds and these additional ingredients gives it a distinct place within the Verum Viridi range.

Selected references

• Citti et al. (2018). Cannabinoid analysis and CBDA decarboxylation.
• Rock et al. (2018). CBDA in a rat model of inflammatory pain.
• Lee et al. (2005). Magnolol and honokiol in cellular inflammatory signalling.
• Phenolic constituents from the stem bark of Magnolia officinalis.